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Physicians usually prescribe B12 for fatigue, as the vitamin converts nutrients from food into glucose, which makes an individual experience a boosted energy level needed for intensive activities

J Neurol Neurosurg Psychiatry 71:371374 Isaacson S, Vernino S, Ziemann A, Rowse GJ, Kalu U, White WB (2016) Long-term safety of droxidopa in patients with symptomatic neurogenic orthostatic hypotension

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Atherosclerosis progression, as a chronic inflammatory mechanism, is characterized by immune system dysregulation associated with increased pro-inflammatory cytokine production, including interleukin 6 (IL-6), tumor necrosis factor- (TNF-), and IL-1 (Vinciguerra et al., 2020